BMAL1 and YAP cooperate to hijack enhancers and promote inflammation in the aged epidermis
Júlia Bonjoch, Paloma Solá, Óscar Reina…·Guiomar Solanas
This study identifies a BMAL1-YAP transcriptional complex that hijacks enhancers in aged epidermis to promote inflammation by rewiring chromatin dynamics and co-regulating inflammation-related genes with NF-KB.