Author

Carolina R. Melo‐Silva

Thomas Jefferson UniversityORCID 0000-0002-0441-5452Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Edilson Torres-GonzáleziD· 1 shared Holly R. RamageiD· 1 shared Jihae ChoiiD· 1 shared Lingjuan TangiD· 1 shared Luis J. SigaliD· 1 shared Marisa I. RomániD· 1 shared Megan KelleriD· 1 shared Michelle GelmaniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Edilson Torres-GonzálezORCID

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1 paper

Recent·Most cited

Interferon-α and -β subtypes have temporally distinct roles in containing viral spread and protecting vital organs.

Carolina R. Melo‐Silva, Marisa I. Román, Natasha Heath, Michelle Gelman, Megan Keller, Jihae Choi, Lingjuan Tang, Oluwatomilola Taiwo, Samita Kafle, Edilson Torres-González, Holly R. Ramage, Raul Andino, Luis J. Sigal

This study shows that IFN-β is critical for survival from ECTV and WNV infections, while IFN-α and other subtypes have distinct roles in controlling viral spread and organ protection.

bioRxiv · Mar 12, 2026 · PreprintImmunology