Metabolism of bilirubin to urobilinogen by human gut bacteria occurs by a branched, multi-enzyme pathway
Baylee J. Russell, Erik Hasenoehrl, Victoria M. Marando, Joy Lu, Jessica Ming Hui Chen, Michael J. James, Mudita Goyal, Suzanne Walker, Seth Rakoff-Nahoum, Marco Jost
This study identifies BilR and BilV as enzymes involved in the branched microbial metabolism of bilirubin to urobilinogen in the human gut.
bioRxiv · Jun 10, 2026 · PreprintMicrobiology