Improving statistical power in severe malaria genetic association studies by augmenting phenotypic precision
James A Watson, Carolyne Ndila, Sophie M. Uyoga, Alexander W. Macharia, Gideon Nyutu, Shebe Mohammed, Caroline Ngetsa, Neema Mturi, Norbert M. Peshu, Benjamin Tsofa, Kirk A. Rockett, Stije J. Leopold, Hugh W. F. Kingston, Elizabeth C. George, Kathryn Maitland, , Nicholas John White
The paper improves statistical power in severe malaria genetic studies by addressing phenotypic imprecision through a probabilistic diagnostic model and data-tilting approach.
eLife · Jul 5, 2021Peer-reviewedGenetics