Author
Centre for Human GeneticsORCID 0000-0002-6369-9299Unclaimed ORCID profile · follow to get notified of new preprints
13 papers
Recent·Most cited
Sanjay Curtis Nagi, Eric R. Lucas, Faisal Ashraf…·Martin J. Donnelly
This paper develops a targeted genomic surveillance approach for insecticide resistance in malaria vectors, identifying resistance variants and demonstrating predictive modeling with high accuracy.
Ellen Miranda Leffler, Gavin Band, Anna E. Jeffreys…·Dominic P. Kwiatkowski
The paper genotypes PIEZO1 STR alleles in malaria cases and controls, finding a modest protective effect of E756del against malaria.
D. Herbert Opi, Carolyne Ndila, Sophie M. Uyoga…·J. Alexandra Rowe
The paper investigates how non-O ABO blood group genotypes relate to Plasmodium falciparum rosetting and severe malaria risk in Kenyan children.
Ryan J. Daniels, María Eugenia D’Amato, Mpasi Lesaoana…·Cristian Capelli
The paper examines genetic heritage of the BaPhuthi to determine if KhoeSan ancestry reflects biological distinction or shared life-way, finding no unique eastern KhoeSan ancestry.
Gavin Band, Ellen Miranda Leffler, Muminatou Jallow…·Dominic P. Kwiatkowski
The paper investigates the association between host sickle cell haemoglobin and parasite genetic variation in malaria severity, finding that parasite alleles linked to HbS show strong linkage disequilibrium and frequency covariation with HbS.
Brandyce St. Laurent, Nick Harding, Nick Deason…·Alistair Miles
The paper uses whole-genome sequencing to analyze genetic diversity and population structure of An. minimus in Cambodia, identifying four distinct populations with unique selection signals.
James A Watson, Carolyne Ndila, Sophie M. Uyoga…·Nicholas John White
The paper improves statistical power in severe malaria genetic studies by addressing phenotypic imprecision through a probabilistic diagnostic model and data-tilting approach.
The Anopheles gambiae 1000 Genomes Consortium, Chris S. Clarkson, Alistair Miles…·Christa Henrichs
The paper analyzes genome variation in 1,142 Anopheles mosquitoes to study population structure and insecticide resistance.
Silvia N. Kariuki, Alejandro Marín-Menéndez, Viola Introini…·Julian C. Rayner
The paper shows that Dantu blood group variant increases red blood cell tension, reducing Plasmodium falciparum invasion and protecting against severe malaria.
Malaria Genomic Epidemiology Network, Gavin Band, Si Quang Le…·Dominic P. Kwiatkowski
This study identifies five genome-wide associations with severe malaria risk in 17,000 individuals from Africa, Asia, and Oceania, including a new variant linked to cerebral malaria.
Oliver John Watson, Lucy Okell, Joel Hellewell…·Robert Verity
This study evaluates genetic metrics for inferring malaria transmission intensity changes using a transmission model and finds one metric can predict prevalence with 0.055 mean absolute error.
Alistair Miles, Chris S. Clarkson, Krzysztof Kozak…·Bronwyn L. MacInnis
The paper sequences genomes of 765 malaria vector mosquitoes to study genetic diversity and insecticide resistance.
Ellen Miranda Leffler, Gavin Band, George Busby…·Malaria Genomic Epidemiology Network
The paper identifies a structural variant in GYPA and GYPB genes associated with reduced risk of severe malaria in sub-Saharan African populations.