Author
Kenya Medical Research InstituteORCID 0000-0001-5364-9610Unclaimed ORCID profile · follow to get notified of new preprints
7 papers
Recent·Most cited
John M. Muriuki, Alexander J. Mentzer, Gavin Band…·Sarah Helen Atkinson
The paper identifies African-specific genetic loci associated with iron status and risk of severe malaria and bacteremia in children, highlighting limited transferability of European polygenic risk scores.
Reagan M. Mogire, John M. Muriuki, Ruth Fiona Bayimenye…·Sarah Helen Atkinson
The paper identifies a novel genetic locus OSBPL11 associated with vitamin D levels and cardiometabolic health in African populations through genome-wide analysis.
Ellen Miranda Leffler, Gavin Band, Anna E. Jeffreys…·Dominic P. Kwiatkowski
The paper genotypes PIEZO1 STR alleles in malaria cases and controls, finding a modest protective effect of E756del against malaria.
D. Herbert Opi, Carolyne Ndila, Sophie M. Uyoga…·J. Alexandra Rowe
The paper investigates how non-O ABO blood group genotypes relate to Plasmodium falciparum rosetting and severe malaria risk in Kenyan children.
Gavin Band, Ellen Miranda Leffler, Muminatou Jallow…·Dominic P. Kwiatkowski
The paper investigates the association between host sickle cell haemoglobin and parasite genetic variation in malaria severity, finding that parasite alleles linked to HbS show strong linkage disequilibrium and frequency covariation with HbS.
James A Watson, Carolyne Ndila, Sophie M. Uyoga…·Nicholas John White
The paper improves statistical power in severe malaria genetic studies by addressing phenotypic imprecision through a probabilistic diagnostic model and data-tilting approach.
Silvia N. Kariuki, Alejandro Marín-Menéndez, Viola Introini…·Julian C. Rayner
The paper shows that Dantu blood group variant increases red blood cell tension, reducing Plasmodium falciparum invasion and protecting against severe malaria.