Modeling cis-regulatory variation in human brain enhancers across a large Parkinson's Disease cohort
Olga M. Sigalova, Alexandra Pančíková, Julie De Man, Koen Theunis, Gert J. Hulselmans, Vasileios Konstantakos, Bram Stuyven, Anton De Brabandere, Jarne Geurts, Antonina Mikorska, Shinjini Mukherjee, Sara Abouelasrar Salama, Katy Vandereyken, Kristofer Davie, Lukas Mahieu, , Stein Aerts
The paper identifies cis-acting genetic variants affecting enhancer function in Parkinson's Disease using multi-omics data and develops models to predict their regulatory impact.
bioRxiv · Apr 16, 2026 · PreprintGenomics