Repurpose of Ritlecitinib Reduces Neointima Formation and Enhances Endothelial Recovery Following Vascular Injury
Dunpeng Cai, Yung-Chun Wang, Lindsey L. Saint, John G. Markley, Shi‐You Chen
This study shows that Ritlecitinib reduces neointima formation and enhances endothelial recovery after vascular injury by modulating JAK3 signaling and VEGF-A/TSP-1 pathways.
bioRxiv · Sep 23, 2025 · PreprintPathology