Sébastien Boutin

This study evaluates real-time metagenomic next-generation sequencing (rt-mNGS) for pathogen detection in respiratory samples, showing non-inferiority to culture methods with higher sensitivity and timely results.

This study shows that mast cell deficiency does not impair immunological protection against sepsis, as Kit-mutant mice are as resistant as wild-type mice, with susceptibility instead due to intestinal dysbiosis.

This study shows combining cefiderocol with aztreonam delays resistance development in NDM-producing E. cloacae complex isolates, with a 4-fold MIC reduction being a key predictor.

This paper predicts decision-making time for diagnosis during NGS cycles using an interpretable machine learning model, achieving over 98% accuracy and reducing turnaround time.