Efficient globin production during terminal erythropoiesis depends on the synergistic action of TENT5C poly(A) polymerase and LARP4/5
Michał Mazur, Natalia Gumińska, Aleksandra Brouze, Dominik Cysewski, Katarzyna Mleczko‐Sanecka, Marta Niklewicz, Monika Kusio-Kobiałka, Andrzej Dziembowski
The paper shows that TENT5C and LARP4/5 work together to maintain globin mRNA poly(A) tails during erythropoiesis, ensuring proper hemoglobin production.
bioRxiv · Nov 14, 2024 · PreprintDevelopmental Biology