Author

David S. Rosenblatt

McGill UniversityORCID 0000-0002-0548-365XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1

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Andreas BergthaleriD· 1 shared Anh Tuấn NguyễniD· 1 shared Anna KoreniD· 1 shared Anne-Sophie M. C. MarquesiD· 1 shared Bettina Gürtl· 1 shared Carol ChengiD· 1 shared Christoph BueschliD· 1 shared D. Sean FroeseiD· 1 shared

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1 shared paperMolecular Biology

Andreas BergthalerORCID

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1 paper

Recent·Most cited

Molecular BiologybioRxivPreprintMar 16, 2025

Functional profiling reveals a non-enzymatic role of NUDT5 in repressing purine de novo synthesis

Jung-Ming G. Lin, Anh Tuấn Nguyễn, Anne-Sophie M. C. Marques…·Stefan Kubicek

The paper identifies a non-enzymatic role of NUDT5 in repressing purine de novo synthesis by scaffolding PPAT, with implications for cancer treatment and MTHFD1 deficiency.

2 citations

humanexperimental assay

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