Lrif1 modulates Trim28-mediated repression of the Dux locus in mouse embryonic stem cells
Darina Šikrová, Román González‐Prieto, Alfred C.O. Vertegaal, Judit Balog, Lucia Daxinger, Silvère M. van der Maarel
This study shows that Lrif1 interacts with Trim28 to repress Dux in mouse embryonic stem cells, linking it to FSHD2 pathogenesis.
bioRxiv · Nov 18, 2024 · PreprintMolecular Biology