Lucia Daxinger

The paper identifies SENP7 and UTF1/VENTX as new loci influencing cPCDH methylation in blood and brain through a genome-wide association study.

This study shows that MORC3 is essential for T cell development in the thymus, as its loss causes developmental arrest and altered chromatin accessibility in DN1 cells.

This study shows that Lrif1 interacts with Trim28 to repress Dux in mouse embryonic stem cells, linking it to FSHD2 pathogenesis.

This study identifies a mutation in SMCHD1 that enhances gene silencing and disrupts developmental processes, revealing distinct roles of SMCHD1 in chromatin structure and gene regulation.

The paper identifies age-related increases in DNA methylation variability on the inactive X chromosome in females and males, with aVMCs accumulating in XCI regions and showing replication in purified cell types.

This study shows that failure to switch from ARID1A-BAF to ARID1B-BAF in patient-derived cells impairs neural crest formation in Coffin-Siris syndrome.

The paper identifies 818 genes influencing DNA methylation in blood using genetic anchors and causal inference, revealing both transcription factors and non-DNA-binding proteins with regulatory roles.

The paper shows Zbtb24 binding prevents promoter methylation and maintains gene activity in mouse embryonic stem cells.