Author

Inga Koneczny

Medical University of ViennaORCID 0000-0002-0567-021XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Cansu Elmas TunciD· 2 shared Francisca FaberiD· 2 shared Fritz ZimprichiD· 2 shared Hakan ÇetiniD· 2 shared Marlene WolfsgruberiD· 2 shared Omar KeritamiD· 2 shared Romana HöftbergeriD· 2 shared Rosa WengiD· 2 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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2 shared papersNeuroscience

Cansu Elmas TuncORCID

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2 papers

Recent·Most cited

A primary human muscle cell-based assay for detecting myasthenia gravis autoantibody binding and assessing AChR cluster impairment

Marlene Wolfsgruber, A. Zimmermann, Katja Starnberger, Tereza Duckova, Omar Keritam, Alexander Woehrleitner, Rosa Weng, Paolo Doksani, Marta Rocha, Nina Matus, Katharina Tripkovic, Minal Pervez, Paloma Fernandes Rosenegger, Francisca Faber, Cansu Elmas Tunc, , Inga Koneczny

This paper establishes a human in vitro neuromuscular junction model to detect and functionally characterize myasthenia gravis autoantibodies with high sensitivity and specificity.

bioRxiv · Aug 15, 2026 · PreprintNeuroscience

Epigenetic dysregulation of Th2 cytokine genes in MuSK myasthenia gravis and its modulation by immunosuppressive therapy

Cansu Elmas Tunc, Andrea Stoccoro, Martina Lari, Farzin Salehi, Veronica Iovino, Alba Cepele, Jennifer Huber, Francisca Faber, Marlene Wolfsgruber, Omar Keritam, Rosa Weng, Anja Steinmaurer, Theresa Koenig, Melania Guida, Hakan Çetin, , Inga Koneczny

This study examines DNA methylation of Th2 cytokine genes in MuSK myasthenia gravis and finds hypomethylation of IL4 and IL13 promoters associated with increased cytokine expression, suggesting epigenetic dysregulation influenced by immunosuppressive therapy.

bioRxiv · Aug 11, 2026 · PreprintImmunology