Martina Lari

This study examines DNA methylation of Th2 cytokine genes in MuSK myasthenia gravis and finds hypomethylation of IL4 and IL13 promoters associated with increased cytokine expression, suggesting epigenetic dysregulation influenced by immunosuppressive therapy.

The paper analyzes paleogenomic data from 5th-6th century Pannonia to reveal genetic diversity and migration patterns in post-Roman communities.

The paper performs whole-exome sequencing on mummified remains to identify a genetic mutation associated with late-onset Pompe disease in a historical figure.

The paper analyzes genomic data from Indigenous groups in Panama to reveal pre-Hispanic demographic changes and the genetic structure of the Isthmo-Colombian area.

The paper analyzes ancient and modern common bean genomes to show that genetic diversity was preserved during early domestication, with significant erosion occurring only recently.

The paper analyzes ancient DNA from the Balearic Islands, Sicily, and Sardinia to trace the arrival and spread of Steppe and Iranian-related ancestries in the western Mediterranean, revealing complex admixture histories.

The paper analyzes mitochondrial DNA from Longobard-era cemeteries to study genetic continuity and admixture during medieval migrations in Europe.

The paper analyzes ancient genomic DNA from two cemeteries associated with the Longobards to study social organization and migration patterns in 6th-century Europe.

Ancient DNA from 223 people (12,000-500 BCE) reveals a west-east hunter-gatherer cline, largely unadmixed farmers, Caucasus-shifted Aegean farmers, and Balkan steppe ancestry almost 2,000 years early.