Defining the host dependencies and the transcriptional landscape of RSV infection and bystander activation
Sara Sunshine, Andreas S. Puschnik, Hanna Retallack, Matthew T. Laurie, Jamin Liu, Duo Peng, Kristeene A. Knopp, Matt S. Zinter, Chun Ye, Joseph L. DeRisi
This study uses CRISPR screening and single-cell RNA sequencing to analyze host factors and transcriptional changes in RSV-infected and bystander cells, revealing distinct gene expression patterns and host dependencies.
bioRxiv · Mar 26, 2025 · PreprintMicrobiology