Matt S. Zinter

The paper analyzes human ascites fluid to identify immune dysregulation features associated with poor outcomes in cirrhosis, finding that B cell dysfunction, not microbial translocation, defines high-risk cases.

This study uses CRISPR screening and single-cell RNA sequencing to analyze host factors and transcriptional changes in RSV-infected and bystander cells, revealing distinct gene expression patterns and host dependencies.

This study shows that macrophage ferroptosis impairs Aspergillus killing in lung transplant recipients, increasing fungal infection risk.

This paper describes a miniaturized and automated method for metagenomic sequencing library preparation that reduces costs and time while maintaining quality.

This paper develops a metagenomic sequencing approach to diagnose lower respiratory tract infections by integrating pathogen detection, microbiome analysis, and host transcriptome data.

This study uses metagenomic sequencing to detect respiratory pathogens in hematopoietic transplant patients, finding it more sensitive than conventional methods and identifying new pathogens.