Matthew T. Laurie

Defining the host dependencies and the transcriptional landscape of RSV infection and bystander activation

This study uses CRISPR screening and single-cell RNA sequencing to analyze host factors and transcriptional changes in RSV-infected and bystander cells, revealing distinct gene expression patterns and host dependencies.

Systematic functional interrogation of SARS-CoV-2 host factors using Perturb-seq

This study uses Perturb-seq to functionally interrogate SARS-CoV-2 host factors in human lung epithelial cells, identifying key factors that influence infection and host response.

On a Robust, Sensitive Cell-Free Method for Pseudomonas Sensing and Quantification

The paper presents a cell-free method for sensing and quantifying the quorum sensing molecule 3OC12HSL in Pseudomonas infections using droplet microfluidics.

Repurposing the quinoline antibiotic nitroxoline to treat infections caused by the brain-eating amoeba Balamuthia mandrillaris

This paper identifies nitroxoline as a potent inhibitor of Balamuthia mandrillaris, showing greater efficacy than current treatments for granulomatous amoebic encephalitis.