The paper investigates how P-element insertions in the long non-coding RNA CR43651 affect piRNA-mediated silencing and fitness in Drosophila melanogaster.

bioRxiv · Jul 17, 2025 · PreprintGenetics

Heterozygous Inversion Breakpoints Suppress Meiotic Crossovers by Altering Recombination Repair Outcomes

Haosheng Li, Erica Berent, Savana Hadjipanteli, Miranda Galey, Nigel Muhammad-Lahbabi, Danny E. Miller, K. Nicole Crown

The paper investigates how heterozygous inversion breakpoints suppress meiotic crossovers and shows that noncrossover gene conversions occur at wildtype levels near breakpoints.

PLoS Genetics · Apr 13, 2023Peer-reviewedGenetics

Natural tolerance to transposition is associated with double-strand break repair and germ-cell differentiation

Jyoti Lama, Satyam P. Srivastav, Sadia Tasnim, Donald Hubbard, Savana Hadjipanteli, Brittny R. Smith, Stuart J. Macdonald, Llewellyn Green, Erin S. Kelleher

The paper identifies genetic variants that confer tolerance to transposition in Drosophila by linking them to double-strand break repair and germline differentiation.

PLoS Genetics · Dec 7, 2022Peer-reviewedGenomics