Molecular BiologyScience AdvancesPeer-reviewed
Gliotoxin, identified from a screen of fungal metabolites, disrupts 7SK snRNP, releases P-TEFb and reverses HIV-1 latency
Mateusz Stoszko, Abdullah M. S. Al‐Hatmi, Anton Škríba…·Tokameh Mahmoudi
The paper identifies gliotoxin as a novel LRA that disrupts 7SK snRNP, releases P-TEFb, and reverses HIV-1 latency in CD4+ T cells.
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