Larger inducible reservoir and higher abundance of exhausted CD8+ T cells in people treated after late versus non-late diagnosis of chronic HIV one year after ART initiation
Kathryn S. Hensley, Liset de Vries, Tanvir Hossain…·Tokameh Mahmoudi
Author
Erasmus MCORCID 0000-0002-1904-6450Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
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Kathryn S. Hensley, Liset de Vries, Tanvir Hossain…·Tokameh Mahmoudi
Yubo Zhang, Vasiliki Matzaraki, Adriana Navas…·Mihai Gheorghe Netea
This study shows that HIV persistence accelerates immune aging in treated individuals, while certain antiretroviral drugs reduce it.
Pien M van Paassen, Alexander O. Pasternak, Dita C. Bolluyt…·Godelieve J. de Bree
Enrico Ne, Raquel Crespo, Ray W. Izquierdo-Lara…·Tokameh Mahmoudi
Catchet-MS identifies thalidomide analogues targeting IKZF1 as novel HIV-1 latency reversal agents by reversing latency in CD4+ T-cells.
Mateusz Stoszko, Abdullah M. S. Al‐Hatmi, Anton Škríba…·Tokameh Mahmoudi
The paper identifies gliotoxin as a novel LRA that disrupts 7SK snRNP, releases P-TEFb, and reverses HIV-1 latency in CD4+ T cells.