Author

Elisa De Crignis

Erasmus MC

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Enrico NeiD· 2 shared Mateusz StoszkoiD· 2 shared Michael D. Röling· 2 shared Raquel CrespoiD· 2 shared Robert-Jan T. S. PalstraiD· 2 shared Tokameh MahmoudiiD· 2 shared Tsung Wai KaniD· 2 shared Abdullah M. S. Al‐HatmiiD· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMolecular Biology

Enrico NeORCID

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2 papers

Recent·Most cited

A two-color haploid genetic screen identifies novel host factors involved in HIV latency

Michael D. Röling, Mahsa Mollapour Sisakht, Enrico Ne, Panagiotis Moulos, Raquel Crespo, Mateusz Stoszko, Elisa De Crignis, Helen C. Bodmer, Tsung Wai Kan, Maryam Akbarzadeh, Vaggelis Harokopos, Pantelis Hatzis, Robert-Jan T. S. Palstra, Tokameh Mahmoudi

This study identifies 10 novel host factors involved in HIV latency using a haploid genetic screen and validates their roles through functional assays and drug testing.

mBio · Dec 7, 2021Peer-reviewedMolecular Biology

Gliotoxin, identified from a screen of fungal metabolites, disrupts 7SK snRNP, releases P-TEFb and reverses HIV-1 latency

Mateusz Stoszko, Abdullah M. S. Al‐Hatmi, Anton Škríba, Michael D. Röling, Enrico Ne, Raquel Crespo, Yvonne M. Mueller, Mohammad Javad Najafzadeh, Joyce Kang, Renata Ptáčková, Elizabeth H LeMasters, Pritha Biswas, Alessia Bertoldi, Tsung Wai Kan, Elisa De Crignis, , Tokameh Mahmoudi

The paper identifies gliotoxin as a novel LRA that disrupts 7SK snRNP, releases P-TEFb, and reverses HIV-1 latency in CD4+ T cells.

Science Advances · Aug 12, 2020Peer-reviewedMolecular Biology