MicrobiologyProceedings of the National Academy of SciencesPeer-reviewed
The HUSH epigenetic repressor complex silences PML nuclear bodies-associated HSV-1 quiescent genomes
Simon Roubille, Tristan Escure, Franceline Juillard…·Patrick Lomonte
This paper identifies the HUSH-SETDB1-MORC2 complex as essential for maintaining HSV-1 latency by promoting H3K9me3 chromatin marks on viral genomes in neurons.