Bacteriophage utilize pseudolysogeny to target non-replicating bacteria and CRISPR-resistant phages eliminate recalcitrant implant infections
Yeswanth Chakravarthy Kalapala, Aditya Kamath Ammembal, Saksham Jain, Nisha Sanjay Barge, Rachit Agarwal
This study shows lytic phages can infect non-replicating bacteria through pseudolysogeny and CRISPR-resistant phages can eliminate persistent Pseudomonas infections in mice.
bioRxiv · Mar 28, 2026 · PreprintMicrobiology