Pharmacology & ToxicologybioRxivPreprint
A humanized 16A antibody conjugated with DNA topoisomerase I inhibitors, targeting a GSTA glycosite-signature epitope.
Yu He, Zhaohui Ji, Wang Nian…·Dapeng Zhou
This paper evaluates the antitumor efficacy of humanized 16A antibody conjugates with DNA topoisomerase I inhibitors, showing potent in vitro and in vivo activity against MUC1-expressing tumors.
DOI 10.1101/2025.03.22.644720