GenomicsMolecular and Cellular BiologyPeer-reviewed
The herpes simplex virus 1 protein ICP4 acts as both an activator and repressor of host genome transcription during infection
Thomas Rivas, James A. Goodrich, Jennifer F. Kugel
This study shows that HSV-1 protein ICP4 both activates and represses host gene transcription by modulating RNA polymerase II occupancy and promoter pausing.
23 citations