James A. Goodrich

The paper uses single-molecule microscopy to show TFIIE subunits dynamically interact with preinitiation complexes, with kinetic changes influenced by TFIIH and disease mutations.

The paper describes methods enabling life science undergraduates to independently design and complete a research project outside of their university setting.

This study shows that HSV-1 protein ICP4 both activates and represses host gene transcription by modulating RNA polymerase II occupancy and promoter pausing.

This study shows miR-206 is critical for myogenesis and identifies new mRNA targets regulated by miR-206 in C2C12 cells.