Nascent RNA profiling reveals regulation of gene transcription through productive reiterative initiation in bacteria
Zhe Sun, Guozhong Huang, Yuqiong Zhang, Shuang Wang, Mikhail Kashlev
The paper develops 5TNET-seq to study productive reiterative initiation in E. coli, finding it occurs in over 51% of promoters and is influenced by specific promoter regions and trinucleotide sequences.
Nucleic Acids Research · Nov 17, 2025Peer-reviewedMicrobiology