Author

Nozomu Obana

University of TsukubaORCID 0000-0002-0637-7904Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 3 Organism:bacteria (other)· 2 Research Focus:cell type annotation· 2 Research Focus:gene regulatory network inference· 2 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:electrophysiology· 1

Frequent Co-Authors

Nobuhiko NomuraiD· 4 shared Masanori ToyofukuiD· 2 shared Akihiro Ninomiya· 1 shared Akihiro OkamotoiD· 1 shared Alexander J. WestermanniD· 1 shared Andrew S. Utada· 1 shared Daisuke HagiwaraiD· 1 shared Divya NaradasuiD· 1 shared

Activity by Year

2020-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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4 shared papersMicrobiology

Nobuhiko NomuraORCID

Mutual co-authors in cluster

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5 papers

Recent·Most cited

Challenging the Diffusion Barrier Paradigm: Biofilms Promote Flavin-mediated Electron Shuttling in Shewanella oneidensis

Yoshihide Tokunou, Yu Manabe, Nozomu Obana, Masanori Toyofuku, Nobuhiko Nomura

This study shows biofilms enhance flavin diffusion in Shewanella oneidensis, challenging the idea that diffusion limits electron transfer in biofilms.

bioRxiv · Dec 4, 2025 · PreprintMicrobiology

3'UTR-derived small RNA couples acid resistance to metabolic reprogramming of Salmonella within macrophages

Takeshi Kanda, Fang Liu, Hoda Kooshapour, Sarah Reichardt, Maolin Wang, Philippe Icyishaka, Nozomu Obana, Alexander J. Westermann, Yanjie Chao, Masatoshi Miyakoshi

This study identifies AdiZ, a small RNA derived from the 3'UTR of adiA mRNA in Salmonella, which regulates metabolic genes and promotes survival in macrophage vacuoles under acidic and hypoxic conditions.

Nucleic Acids Research · Nov 19, 2025Peer-reviewedMicrobiology

Development of the genetic toolkit identifies capsular polysaccharides as a competitive colonization factor in Ruminococcus gnavus

Nozomu Obana, Gaku Nakato, Nobuhiko Nomura, Shinji Fukuda

This study develops genetic tools for Ruminococcus gnavus to identify capsular polysaccharides as a factor enhancing colonization and linked to inflammatory bowel disease.

bioRxiv · Aug 12, 2025 · PreprintMicrobiology

Droplet Sequencing Reveals Virulence Gene Clusters in Oral Biofilm Extracellular Vesicles

Sotaro Takano, Divya Naradasu, Satoshi Takenawa, Kangmin Yan, Tomoko Maehara, Nobuhiko Nomura, Nozomu Obana, Masanori Toyofuku, Michihiko Usui, Wataru Ariyoshi, Akihiro Okamoto

This paper introduces a microdroplet-based sequencing technique to analyze DNA content in individual bacterial extracellular vesicles, revealing gene clusters related to virulence and horizontal gene transfer in oral biofilms.

bioRxiv · Sep 18, 2024 · PreprintMicrobiology

Fungal mycelia and bacterial thiamine establish a mutualistic growth mechanism

Gayan Abeysinghe, Momoka Kuchira, Gamon Kudo, Shunsuke Masuo, Akihiro Ninomiya, Kohei Takahashi, Andrew S. Utada, Daisuke Hagiwara, Nobuhiko Nomura, Naoki Takaya, Nozomu Obana, Norio Takeshita

This study identifies a mutualistic mechanism between Aspergillus nidulans and Bacillus subtilis where bacterial thiamine supports fungal growth and fungal mycelia enable bacterial dispersal.

Life Science Alliance · Sep 22, 2020Peer-reviewedMicrobiology