Author

Claire S. Laxton

Yale UniversityORCID 0000-0002-0642-2015Unclaimed ORCID profile · follow to get notified of new preprints

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Claire S. Laxton1 paper

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Anne L. WyllieiD· 2 shared Femke L. ToekiraniD· 2 shared Orchid M. AllicockiD· 2 shared Tzu-Yi LiniD· 2 shared Alidia M. KoelewijniD· 1 shared Anna YorkiD· 1 shared Beta D. Lomeda· 1 shared Chikondi PenoiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersMicrobiology

Anne L. WyllieORCID

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2 papers

Recent·Most cited

Storage stability of non-encapsulated pneumococci in saliva is dependent on null-capsule clade, with strains carrying aliC and aliD showing a competitive disadvantage during culture enrichment

Claire S. Laxton, Orchid M. Allicock, Chikondi Peno, Tzu-Yi Lin, Alidia M. Koelewijn, Femke L. Toekiran, Luna Aguilar, Anna York, Anne L. Wyllie

This study evaluates the storage stability of non-encapsulated pneumococci in saliva, finding that NCC2 strains are less stable than NCC1, and that extraction-free methods may better detect NCC2 strains.

Microbiology · Aug 1, 2025Peer-reviewedMicrobiology

An abundance of aliC and aliD genes were identified in saliva using a novel multiplex qPCR to characterize group II non-encapsulated pneumococci with improved specificity

Claire S. Laxton, Femke L. Toekiran, Tzu-Yi Lin, Beta D. Lomeda, Maikel S. Hislop, Lance E. Keller, Orchid M. Allicock, Anne L. Wyllie

The paper develops a novel multiplex qPCR assay to detect and classify non-encapsulated pneumococci (NESp) by targeting aliC and aliD genes, showing high specificity and prevalence in saliva samples.

Microbiology · Apr 25, 2025Peer-reviewedMicrobiology