Author

Anna York

Yale UniversityORCID 0000-0002-1332-8983Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Anne L. WyllieiD· 2 shared Chrispin ChaguzaiD· 2 shared Daniel M. WeinbergeriD· 2 shared Stephanie W. LoiD· 2 shared Stephen D. BentleyiD· 2 shared Akuzike Kalizang’omaiD· 1 shared Alidia M. KoelewijniD· 1 shared Amelieke J. H. CremersiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersMicrobiology

Anne L. WyllieORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

The global evolutionary dynamics of natural capsule switching in a human-restricted bacterial pathogen

Chrispin Chaguza, Anna York, Stephanie W. Lo, Akuzike Kalizang’oma, Rebecca A. Gladstone, Brenda Kwambana-Adams, Rory J. Cave, Keith P. Klugman, Cheryl P. Andam, Robert S. Heyderman, Lesley McGee, Jason W. Rosch, Nicholas J. Croucher, Stephen D. Bentley, Daniel M. Weinberger

This study examines capsule switching in Streptococcus pneumoniae using whole-genome sequences, finding that switching is limited to specific capsule-type pairs and influenced by genetic and ecological factors.

bioRxiv · Sep 30, 2026 · PreprintMicrobiology

The capsule and genetic background, rather than specific individual loci, strongly influence in vitro pneumococcal growth kinetics

Chrispin Chaguza, Daan W Arends, Stephanie W. Lo, Indri Hapsari Putri, Anna York, John A. Lees, Anne L. Wyllie, Daniel M. Weinberger, Stephen D. Bentley, Marien Isaäk de Jonge, Amelieke J. H. Cremers

This study shows that pneumococcal growth kinetics are influenced by capsular serotype, lineage, and genetic background rather than specific loci.

eLife · Oct 21, 2025Peer-reviewedMicrobiology

Storage stability of non-encapsulated pneumococci in saliva is dependent on null-capsule clade, with strains carrying aliC and aliD showing a competitive disadvantage during culture enrichment

Claire S. Laxton, Orchid M. Allicock, Chikondi Peno, Tzu-Yi Lin, Alidia M. Koelewijn, Femke L. Toekiran, Luna Aguilar, Anna York, Anne L. Wyllie

This study evaluates the storage stability of non-encapsulated pneumococci in saliva, finding that NCC2 strains are less stable than NCC1, and that extraction-free methods may better detect NCC2 strains.

Microbiology · Aug 1, 2025Peer-reviewedMicrobiology