Author

Felix Kleefeld

Humboldt-Universität zu BerlinORCID 0000-0002-0643-7313Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Andreas HentscheliD· 1 shared Andreas RoosiD· 1 shared Andrew Lee MammeniD· 1 shared Anne SchänzeriD· 1 shared Benedikt G. H. SchoseriD· 1 shared Christopher NelkeiD· 1 shared Corinna PreußeiD· 1 shared Daniel LagosiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Andreas HentschelORCID

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1 paper

Recent·Most cited

Mitochondrial leakage and mtDNA damage trigger early immune response in Inclusion Body Myositis.

Felix Kleefeld, Emily Cross, Daniel Lagos, Benedikt G. H. Schoser, Andreas Hentschel, Tobias Ruck, Christopher Nelke, Sara Walli, Katrin Hahn, Denisa Hathazi, Andrew Lee Mammen, María Casal-Domínguez, Marta Ortova Gut, Ivo Glynne Gut, Simon Charles Heath, , Rita Horváth

This study identifies mitochondrial dysfunction and mtDNA damage as early triggers of immune response in PM-Mito and IBM, linking mitochondrial abnormalities to inflammation and disease progression.

bioRxiv · Aug 5, 2024 · PreprintNeuroscience