Marta Ortova Gut

Manta and devil ray genome assemblies uncover signatures of pelagic adaptation

The paper generates high-quality genome assemblies for two manta and devil ray species and identifies structural variations linked to pelagic adaptation.

Pdk1-dependent metabolic heterogeneity promotes aggressive colorectal cancer through cell-intrinsic interferon signaling

This study identifies Pdk1-high metabolic cancer cells in colorectal tumors that drive aggressive behavior through interferon signaling.

ERGA-BGE genome of Valencia hispanica (Valenciennes, 1826): a critically endangered Iberian toothcarp

The paper presents the chromosome-level genome assembly of Valencia hispanica, a critically endangered fish, to support conservation and ecological studies.

Modulation of Avian Iridescence via Melanogenesis

This study identifies melanogenesis gene mutations that alter feather photonic nanostructures, causing iridescent color changes in peafowl and wild birds.

Ancient whole genomes reveal regional selection during adaptation to Neolithic lifestyle in Western Eurasia

This study uses ancient whole-genome data to show geographically structured selection during the Neolithic transition in Western Eurasia, involving both farmer and hunter-gatherer alleles.

EpiATLAS - a reference for human epigenomic research

EpiATLAS provides a comprehensive collection of human reference epigenomes to advance epigenomic research and understanding of cellular function and disease.

ERGA-BGE reference genomes of Hyalomma lusitanicum and its obligate Francisella endosymbiont as a genomic resource for One Health research

The paper presents genomic resources for Hyalomma lusitanicum and its Francisella endosymbiont, providing insights into host-symbiont evolution and disease transmission.

Non-invasive genomic sampling uncovers novel connectivities and origins of confiscated gorillas

This study uses non-invasive genomic sampling to analyze genetic diversity in wild gorillas, revealing population clusters and migration patterns, and predicts geographic origins with high accuracy.

Chromoanagenesis is a driver of structural variationin the smallest photosynthetic eukaryote

The paper shows that resistance to a virus in Ostreococcus mediterraneus evolves rapidly through chromoplexy-driven structural variations on a single chromosome, without consistent SNPs or shared structural variants.

Early downregulation of hair cell (HC)-specific genes in the vestibular sensory epithelium during chronic ototoxicity

The paper identifies gene expression changes in the vestibular sensory epithelium during chronic ototoxicity, finding early downregulation of HC-specific genes and upregulation of stress mediators across species and compounds.

ERGA-BGE genome of Stigmatoteuthis arcturi Robson, 1948: the jewelled squid

The paper presents the chromosome-level genome assembly of Stigmatoteuthis arcturi, providing insights into the evolutionary biology of deep-sea squids.

Over-expression and increased copy numbers of a cytochrome P450 and two UDP-glucuronosyltransferase genes in macrocyclic lactone resistant Psoroptes ovis of cattle

The paper identifies over-expression and copy number variation of cytochrome P450 and UDP-glucuronosyltransferase genes in ML-resistant Psoroptes ovis mites from cattle.

Dorsal Striatum Parvalbumin interneurons translatome unveiled

The paper profiles the translatome of dorsal striatum PV interneurons, identifying molecular signatures and gene expression changes linked to psychostimulant exposure and reward behaviors.

The genomic landscape of spider monkeys and northern muriquis from a conservation perspective

The paper analyzes the genomes of spider monkeys and northern muriquis to assess genetic diversity, load, and divergence, finding no alignment between genetic diversity and endangerment status, higher genetic load in wild populations, and divergence linked to environmental factors.

ERGA-BGE genome of Coenonympha oedippus: an IUCN endangered European butterfly species occurring in two ecotypes

The paper presents the reference genome of Coenonympha oedippus, an endangered butterfly, to study genetic mechanisms of adaptation to two ecotypes and support conservation efforts.

ERGA-BGE Reference Genome of Loboptera subterranea: a cave adapted cockroach endemic to the Canary Islands

The paper presents the genome assembly of Loboptera subterranea, a cave-adapted cockroach, providing insights into its adaptation to subterranean environments.

Chromosome-level genome assembly and annotation of Corallium rubrum: a Mediterranean coral threatened by overharvesting and climate change.

This paper presents the first chromosome-level genome assembly and annotation for the red coral Corallium rubrum, providing genomic resources for conservation and population genomics studies.

ERGA-BGE Reference Genome of Phyllidia flava (Nudibranchia: Phyllidiidae), a Relict Species Endemic to the Mediterranean Sea

The paper presents a chromosome-level reference genome for Phyllidia flava, a Mediterranean nudibranch, to aid conservation and phylogenetic studies.

ERGA-BGE genome of Erebia palarica Chapman, 1905: a montane butterfly endemic to North-West Iberia

The paper presents the reference genome of Erebia palarica, enabling studies on speciation, hybridization, and population genetics.

ERGA-BGE genome of the Spanish Moon Moth Graellsia isabellae Graells, 1849: a nocturnal lepidopteran protected by the Habitats Directive

The paper presents the reference genome of the Spanish Moon Moth Graellsia isabellae, which helps resolve its scientific name and supports genetic monitoring of the species.

ERGA-BGE Reference Genome of the Striped Field Mouse (Apodemus agrarius), a Widespread and Abundant Species in Central and Eastern Europe

The paper presents a chromosome-level reference genome for the striped field mouse, providing resources for phylogenetic studies and understanding its geographical distribution.

ERGA-BGE Reference Genome of Gluvia dorsalis: An Endemic Sun Spider from Iberian Arid Regions

The paper presents the first reference genome of Gluvia dorsalis, a sun spider, providing insights into its adaptation to arid environments and arachnid evolution.

ERGA-BGE Reference Genome of the Northern chamois (Rupicapra rupicapra): Europe's most abundant mountain ungulate

The paper presents a chromosome-level reference genome for the Northern chamois, providing insights into its genetic adaptation to extreme environments.

Comprehensive reanalysis for CNVs in exome sequencing data from unsolved rare disease cases results in new diagnoses

The paper reanalyzes exome sequencing data from rare disease cases to identify previously undetected copy number variants, resulting in diagnoses for 51 families and partial explanations for 34 individuals.

The European Reference Genome Atlas: piloting a decentralised approach to equitable biodiversity genomics

The paper describes the European Reference Genome Atlas (ERGA) pilot project, which tests a decentralized model for producing high-quality reference genomes across 98 European species.

The Draparnaldia genome: alternative mechanisms for multicellularity and terrestrialization in green plants

This study sequenced the Draparnaldia genome and transcriptomes, revealing expanded gene families linked to multicellularity and terrestrial adaptations, and its ability to synthesize phytohormones used by land plants.

Mitochondrial leakage and mtDNA damage trigger early immune response in Inclusion Body Myositis.

This study identifies mitochondrial dysfunction and mtDNA damage as early triggers of immune response in PM-Mito and IBM, linking mitochondrial abnormalities to inflammation and disease progression.

A chromosome-level reference genome for the common octopus, Octopus vulgaris (Cuvier, 1797)

The paper presents a chromosome-level genome assembly for the common octopus, O. vulgaris, which spans 2.8 billion basepairs and supports a karyotype of 1n=30 chromosomes.

The landscape of tolerated genetic variation in humans and primates

The paper uses primate genetic data to predict human variant pathogenicity with a deep learning classifier trained on 4.3 million common missense variants.

A global catalog of whole-genome diversity from 233 primate species

This study presents whole-genome data from 233 primate species, revealing patterns of genetic diversity, mutation rates, and recurrent missense mutations across primate clades.