Michael Desgagné

The paper identifies β-Klotho as a novel substrate of TMPRSS6, showing that TMPRSS6 cleavage reduces KLB surface abundance and attenuates FGF19 signaling, linking TMPRSS6 to hepatic lipid metabolism.

ATOMICA learns transferable representations of intermolecular interactions across diverse molecular types, enabling cross-modal comparisons and experimentally testable hypotheses.