Maria A. Holland

Wall stiffening is a primary contributor to motility loss in Crohn's disease: an electromechanical modeling study

This study uses an electromechanical model to show that wall stiffening is the main cause of motility loss in Crohn's disease fibrotic strictures, with smooth-muscle contractility as the next major factor.

Modeling Inflammation-Driven Colon Hypertrophy and Motility Changes in Gulf War Illness

The paper develops a computational model to simulate inflammation-driven colon hypertrophy and motility changes in Gulf War Illness using PB-exposed mouse data.

Inference of self-limiting neutrophil swarming dynamics using Bayesian physics-informed neural networks

The paper develops a Bayesian physics-informed neural network to model neutrophil swarming dynamics in human and murine cells, revealing species-specific differences in recruitment and self-limitation.

A Biophysical Model of Human Colonic Motor Pattern Generation in Health and Disease

This paper develops a biophysical model of human colonic motor patterns that reproduces healthy and disease states, showing how parameters affect motility.

Compensating Cortical Thickness for Cortical Folding-Related Variation

This paper develops a method to compensate for cortical folding effects on cortical thickness, improving its biological interpretability and reducing variability in brain morphology studies.

Astrocytes in white matter respond to tensile cues during cortical folding: a numerical study

This paper investigates how astrocytes influence cortical folding through tensile cues, finding that their proliferation in response to tension leads to deeper folds.