Eduardo Reátegui

Inference of self-limiting neutrophil swarming dynamics using Bayesian physics-informed neural networks

The paper develops a Bayesian physics-informed neural network to model neutrophil swarming dynamics in human and murine cells, revealing species-specific differences in recruitment and self-limitation.

Single Particle Adsorption and Response Quantification for Functional AAVx Titer and Dose Analysis

This paper introduces SPARQ, a method to quantify functional AAV vectors at single-particle resolution, revealing functional heterogeneity and improving dose analysis in gene therapy.

Multidimensional Cellular Micro-Compartments to Model Invasive Lobular Carcinoma Dormancy

This study develops multidimensional in vitro models to investigate anti-estrogen resistance and dormancy in invasive lobular carcinoma, identifying p27Kip1 signaling as central to dormant phenotype.

Light-induced Extracellular Vesicle Adsorption

This paper introduces LEVA, a label-free, high-resolution, tunable platform for EV adsorption and characterization, demonstrating its versatility with various EV sources and applications.

Human differentiated adipocytes can serve as surrogate mature adipocytes for adipocyte-derived extracellular vesicle analysis

The paper shows that human differentiated adipocytes can produce EVs similar to mature adipocytes, providing a reliable alternative for studying adipocyte-derived extracellular vesicles in obesity research.

Integrated Techniques for Extracellular Particle Separation and Single-Particle Multiparametric Characterization to Track Cancer Biomarkers from Tissue to Biofluids

This study uses BEST and MBA to track extracellular vesicle cargo in gastric cancer, showing saliva as the best biofluid for diagnosis.

Novel multiparametric bulk and single extracellular vesicle pipeline for adipose cell-specific biomarker discovery in paired human biospecimens

The paper develops a multiparametric pipeline to isolate and characterize adipose-derived extracellular vesicles from human biospecimens, identifying cell-specific biomarkers and pathways associated with obesity.