Mitophagy-related prohibitin 2 is an orthoflavivirus restriction factor targeted for degradation during infection
Imanol Rodrigo, María José Romero de Ávila, Belén García-Navarro, Martín Arellano, Laura Albentosa-González, Pilar Clemente-Casares, Edward Emmott, Armando Arias
This paper identifies prohibitin 2 (PHB2) as an orthoflavivirus restriction factor that is targeted for degradation during infection to enhance viral replication.
bioRxiv · Feb 12, 2026 · PreprintMicrobiology