Author

Thea B. Gessler

Iowa State UniversityORCID 0000-0002-0701-0389Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Organism:chicken / avian· 1 Research Focus:dimensionality reduction· 1 Research Focus:gene regulatory network inference· 1 Organism:multiple species· 1

Frequent Co-Authors

Nicole ValenzuelaiD· 2 shared Abigail RalstoniD· 1 shared Basanta BistaiD· 1 shared Christopher ZdyrskiiD· 1 shared David Kyle MeyerholziD· 1 shared Dean C. AdamsiD· 1 shared Debosmita KunduiD· 1 shared Dipak Kumar SahooiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersEvolutionary Biology

Nicole ValenzuelaORCID

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2 papers

Recent·Most cited

Gene-transcription factor regulatory networks implicate primary cilia in the evolution of vertebrate sex determination and expand models of epigenetic regulation

Thea B. Gessler, Dean C. Adams, Nicole Valenzuela

This paper models regulatory networks in turtles with different sex determination mechanisms to identify evolutionary changes in gene regulation and highlights the role of primary cilia in TSD.

PLoS ONE · Jul 29, 2026Peer-reviewedEvolutionary Biology

Characterization of the First Turtle Organoids: A Model for Investigating Unique Adaptations with Biomedical Potential

Christopher Zdyrski, Vojtěch Gabriel, Thea B. Gessler, Abigail Ralston, Itzel Sifuentes‐Romero, Debosmita Kundu, Sydney T. Honold, Hannah Wickham, Nicholas E. Topping, Dipak Kumar Sahoo, Basanta Bista, Jeffrey W. Tamplin, Oscar E. Ospina, Pablo Enrique Piñeyro, Marco A. Arriaga, , Nicole Valenzuela

The paper develops the first turtle-derived hepatic organoids from multiple species, enabling in vitro studies of unique adaptations and biomedical applications.

Communications Biology · Feb 22, 2024Peer-reviewedGenetics