Neil R. Hardingham

This study shows that both primary and secondary somatosensory cortices are required for whisker-based texture discrimination learning in mice, with S2 feedback modulating LTP in S1 and inducing structural plasticity in S1 basal dendrites.

The paper investigates plasticity mechanisms in two types of layer 5 neurons in the visual cortex of mice, finding distinct Hebbian and homeostatic properties in RS and IB cells.