The native cell differentiation program aberrantly recapitulated in yki3S/A-induced intestinal hyperplasia drives invasiveness and cachexia-like wasting phenotypes
Inez K.A. Pranoto, Jiae Lee, Young V. Kwon
This study shows that a native differentiation program in intestinal tumors drives invasiveness and cachexia-like wasting by recapitulating enterocyte development in Drosophila.
bioRxiv · Jun 1, 2022 · PreprintDevelopmental Biology