Young V. Kwon

Comparison of Techniques for Isolating Small Extracellular Vesicles from Drosophila Larval Hemolymph

This study compares three methods for isolating small EVs from Drosophila larval hemolymph, finding that size-exclusion chromatography yields the purest fractions but lowest protein yield.

A Modular Platform for Purification of Organelle-associated Mitochondria Reveals Functional Specialization at Organelle Contact Sites

The paper introduces ORCA, a method to isolate mitochondria associated with specific organelles, revealing distinct proteomes and functional roles at organelle contact sites.

Mitochondrial metabolic remodeling drives innate immune activation in Drosophila hemocytes

This study shows that mitochondrial metabolic reprogramming is essential for innate immune activation in Drosophila hemocytes, linking mitochondrial dynamics to immune responses.

The native cell differentiation program aberrantly recapitulated in yki3S/A-induced intestinal hyperplasia drives invasiveness and cachexia-like wasting phenotypes

This study shows that a native differentiation program in intestinal tumors drives invasiveness and cachexia-like wasting by recapitulating enterocyte development in Drosophila.

Wear and Tear of the Intestinal Visceral Musculature by Intrinsic and Extrinsic Factors

The paper investigates how intrinsic and extrinsic factors disrupt the gut visceral musculature in Drosophila and zebrafish, identifying four phenotypes as indicators of musculature deterioration.