Alan G. Barbour

Xist expression in male Peromyscus leucopus is associated with restricted chromatin repression and incomplete X-to-autosome dosage compensation

This study identifies robust Xist expression in male Peromyscus leucopus somatic cells, showing gene-selective repression rather than global X-chromosome inactivation.

SARS-CoV-2 virus infection of Peromyscus leucopus demonstrates that infection tolerance is not limited to agents for which deermice are reservoirs

This study infects deermice with SARS-CoV-2 to show infection tolerance extends to novel pathogens, with limited inflammation and effective immune control.

Dermal fibroblast cultures recapitulate differences between deermice and mice in responses to a Toll-like receptor agonist

The paper uses fibroblast cultures from deermice and mice to show differences in innate immune responses and ERV/TE activation to TLR agonists.

The utility of a closed breeding colony of Peromyscus leucopus for dissecting complex traits

The paper evaluates the utility of a closed Peromyscus leucopus colony for dissecting complex traits using low-pass sequencing and simulations, finding modest QTL detection power but potential for extension to other colonies.

The infection-tolerant mammalian reservoir of Lyme disease and other zoonoses broadly counters the inflammatory effects of endotoxin

This study compares the inflammatory responses of two rodent species to LPS, finding differences in cytokine profiles and metabolic pathways that suggest infection tolerance mechanisms in the deermouse.