Landen Gozashti

This study constructs a pangenome for deer mice to reveal extensive structural variation and its evolutionary implications.

The paper estimates an extreme transmission bottleneck in a deep-sea clam symbiosis using ultra-accurate sequencing, finding an effective bottleneck size of about eight symbionts per host generation.

This study identifies 35.3 million structural variants across vertebrates, showing significant variation in their abundance, mechanisms, and functional impact across species.

This study identifies two melanic pigmentation patterns in Xiphophorus nezahualcoyotl linked to the sex chromosome-linked oncogene xmrk through long-read sequencing and GWAS.

The paper identifies splicing deficiency in non-recombining mating-type chromosomes across phytoplankton species, showing how recombination suppression leads to transcript-level dysfunction.

The paper directly identifies de novo mobile element insertions in human sperm using long-read sequencing and finds age-related increases in retrotransposition rates.

The paper uses fibroblast cultures from deermice and mice to show differences in innate immune responses and ERV/TE activation to TLR agonists.

The paper identifies intron-generating transposons in viral elements, suggesting dsDNA viruses may facilitate horizontal transfer of introners between species.

The paper identifies horizontal transfer of intron-containing transposons as a major source of new introns across eukaryotic lineages.

This study analyzes the olfactory genome of deer mice to reveal conserved and divergent components of the rodent olfactory subgenome and their evolutionary implications.

The paper presents T2T mouse genomes for C57BL/6J and CAST/EiJ, revealing structural diversity in telomeres, centromeres, and key loci like PAR and KZFPs.

This study identifies thousands of chromosomal inversions in deer mice and shows that repeats, particularly centromeric satellite arrays, drive large-scale genomic rearrangements.

The paper identifies universal patterns of transposable element (TE) compartmentalization across eukaryotic genomes, linking TEs to gene families under selective pressure and adaptive functions.

The paper identifies Introners, transposable elements driving intron gain in diverse eukaryotes, and finds they are prevalent in marine species and phylogenetically distant lineages.

The paper examines the unique TE landscape in deer mice, showing LTR retrotransposons dominate over LINEs due to ERV invasion and KZNF gene expansion.

The paper introduces UShER, a method for ultrafast phylogenetic placement of SARS-CoV-2 sequences, enabling real-time genomic contact tracing and maintaining an updated reference phylogeny.

The paper identifies lab-specific recurrent mutations in SARS-CoV-2 sequences that affect phylogenetic inference and proposes tools to improve sequence quality and phylogeny comparison.

The paper studies intron evolution in dinoflagellates, revealing a high diversity of intron-creating transposable elements and complex spliceosomal system transformations.