Assembly of von Willebrand Factor Tubules with in Vivo Helical Parameters Requires A1 Domain Insertion
Gabriel Javitt, Noa Yeshaya, Lev Khmelnitsky, Deborah Fass
The paper shows the A1 domain is necessary for forming VWF helical tubules matching those in Weibel-Palade bodies and plays a role in intracellular assembly.
Blood · Sep 30, 2022Peer-reviewedMolecular Biology