Deborah Fass

The paper develops hMultiCLEM, a high-resolution screening pipeline combining EM and multiplexed human cell pools to identify proteins affecting mitochondrial cristae shape, uncovering MISHA linked to Meniere's disease.

The paper shows the A1 domain is necessary for forming VWF helical tubules matching those in Weibel-Palade bodies and plays a role in intracellular assembly.

The paper shows that the SLS pathway in Trypanosoma brucei is triggered by disruptions in ER, Golgi, or mitochondrial protein handling and identifies PK3 phosphorylation as critical for its activation.

The paper presents an integrated structural analysis of intestinal mucin MUC2, revealing the shared mechanism of polymer formation for mucosal barriers and blood clotting.