Ron Diskin

The paper identifies a broadly neutralizing antibody against multiple orthoebolaviruses from an rVSV-EBOV vaccinated individual and shows its protective efficacy in animal models.

The paper designs structurally diverse antibody repertoires with drug-like properties using a computational method called CADAbRe, demonstrating their utility in binding to challenging targets.

The paper determines the structure of the Sabia virus spike complex and shows potassium and acidic pH induce conformational changes necessary for cell entry.

This paper determines the trimeric structure of the HERV-K Env spike using cryo-EM, revealing insights into its function and evolutionary relationships.

The paper determines the cryo-EM structure of the Lujo virus spike complex, revealing how it binds neuropilin-2 and providing insights for vaccine design.

This paper determines the homodimeric structure of LARGE1, a glycosyltransferase, revealing its dimerization mechanism and how disease mutations affect its function.

The paper studies how two antibodies recognize the glycan antigen CA19-9 using crystallography and computational methods to improve antibody affinity.

The paper presents an integrated structural analysis of intestinal mucin MUC2, revealing the shared mechanism of polymer formation for mucosal barriers and blood clotting.