Author

Daniël M. Miedema

The Netherlands Cancer InstituteORCID 0000-0002-0729-3753Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1 Research Focus:trajectory inference· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Annegien BroeksiD· 1 shared Bauke YlstraiD· 1 shared Beatriz G. CarvalhoiD· 1 shared Christian R. RauschiD· 1 shared Dennis D. G. C. PetersiD· 1 shared Erik van DijkiD· 1 shared Iris M. SeignetteiD· 1 shared Johanna Wilhelmina van SandickiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBioinformatics

Annegien BroeksORCID

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1 paper

Recent·Most cited

Karyotype Evolution in Response to Chemoradiotherapy and Upon Recurrence of Esophageal Adenocarcinomas.

Karen van der Sluis, Johanna Wilhelmina van Sandick, Willem J. Koemans, Tom van den Bosch, Annegien Broeks, Dennis D. G. C. Peters, Iris M. Seignette, Christian R. Rausch, Erik van Dijk, Pétur Snæbjörnsson, José G. van den Berg, Nicole C.T. van Grieken, Bauke Ylstra, Beatriz G. Carvalho, Daniël M. Miedema, Liudmila L. Kodach

This study tracks karyotype evolution in esophageal adenocarcinomas during chemoradiotherapy and recurrence, showing that treatment-induced copy number aberrations predict early recurrence and are partially reversed upon recurrence.

Cell Reports · Nov 1, 2024Peer-reviewedBioinformatics