Author

Christian R. Rausch

German Cancer Research CenterORCID 0000-0002-7364-5526Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:variant calling· 2 Research Focus:cell type annotation· 1 Approach:experimental assay· 1

Frequent Co-Authors

Adrian GottschlichiD· 1 shared Adrien DaigeleriD· 1 shared Anand S. BhagwatiD· 1 shared Andrew StubbsiD· 1 shared Anne S. Bolijn· 1 shared Annegien BroeksiD· 1 shared Arman ÖneriD· 1 shared Bart J. JansseniD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperImmunology

Adrian GottschlichORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A CAR T cell-amplified suppressive B cell circuit in AML

Adrian Gottschlich, Vladyslav Kavaka, Thomas Alexander Janert, Veronika Igl, Emanuele Carlini, Lisa Rohrbacher, Wendy den Hartog, Jakob Harwood, Marcel P. Trefny, Selin Sogukcelik, Philipp Penovici, Bernhard Ransmayr, Christian R. Rausch, Franziska Brauneck, Stephanie Frenz-Wiessner, , Sebastian Kobold

The paper identifies suppressive atypical memory B cells in AML that are amplified by CAR T cell interactions and shows that targeting both B cells and AML blasts can overcome this suppression.

bioRxiv · Oct 21, 2026 · PreprintImmunology

Karyotype Evolution in Response to Chemoradiotherapy and Upon Recurrence of Esophageal Adenocarcinomas.

Karen van der Sluis, Johanna Wilhelmina van Sandick, Willem J. Koemans, Tom van den Bosch, Annegien Broeks, Dennis D. G. C. Peters, Iris M. Seignette, Christian R. Rausch, Erik van Dijk, Pétur Snæbjörnsson, José G. van den Berg, Nicole C.T. van Grieken, Bauke Ylstra, Beatriz G. Carvalho, Daniël M. Miedema, Liudmila L. Kodach

This study tracks karyotype evolution in esophageal adenocarcinomas during chemoradiotherapy and recurrence, showing that treatment-induced copy number aberrations predict early recurrence and are partially reversed upon recurrence.

Cell Reports · Nov 1, 2024Peer-reviewedBioinformatics

Detection of fusion transcripts and their genomic breakpoints from RNA sequencing data

Youri Hoogstrate, Malgorzata A. Komor, René Böttcher, Job van Riet, Harmen J.G. van de Werken, Stef van Lieshout, Ralf Hoffmann, Evert van den Broek, Anne S. Bolijn, Natasja F. J. Dits, Daoud Sie, David van der Meer, Floor Pepers, Chris H. Bangma, Geert J.L.H. van Leenders, , Guido W Jenster

Dr. Disco identifies fusion transcripts and genomic breakpoints using non poly(A)-enriched RNA-seq data, revealing transcribed rearrangements and their expression effects in cancer samples.

bioRxiv · May 17, 2021 · PreprintBioinformatics