Natalie Suff

Ascending vaginal infection in mice induces preterm birth and neonatal morbidity

This study shows that ascending vaginal E. coli infection in pregnant mice causes preterm birth and neonatal morbidity, with validated therapeutic potential for cervical gene therapy.

Generation of light-producing somatic-transgenic mice using adeno-associated virus vectors

The paper develops a method using adeno-associated virus vectors to generate somatic-transgenic mice for non-invasive monitoring of signaling pathways in disease models.

Gene therapy in argininosuccinic aciduria

This paper demonstrates that gene therapy using AAV8 vector corrects urea cycle and citrulline-NO cycle defects in ASL-deficient mice, reducing neuronal disease and improving behavior.