Author

Els Henckaerts

KU LeuvenORCID 0000-0002-4624-7856Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Adrián G. PalaciosiD· 1 shared Ahad A. RahimiD· 1 shared Álvaro O. ArdilesiD· 1 shared Andrew M.S. Wong· 1 shared Bram VandewinkeliD· 1 shared Claudia Sepúlveda-Quiñenao· 1 shared Claudio A. HetziD· 1 shared Dany P.B. PerocheauiD· 1 shared

Activity by Year

2020-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperCell Biology

Adrián G. PalaciosORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Cell BiologybioRxivPreprintAug 12, 2026

Optimized AAV to express the unfolded protein response transcription factor XBP1s ameliorates Alzheimer's disease features in mouse models

Mei Li Díaz, Giovanni Tamburini, Diego Arriagada…·Claudio A. Hetz

This study develops a next-generation AAV vector expressing optimized XBP1s to improve proteostasis, reducing Alzheimer's disease features in mouse models.

DOI 10.64898/2026.08.11.743979

mouseexperimental assay

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Cell BiologyPLoS PathogensPeer-reviewedMar 10, 2026

The adeno-associated virus Rep proteins target PP4:SMEK1 by preventing substrate-recruitment

Bram Vandewinkel, Sophie Torrekens, Zander Claes…·Els Henckaerts

This study identifies PP4:SMEK1 as a host restriction factor suppressed by AAV Rep proteins through substrate-recruitment interference, enhancing rAAV vector potency.

DOI 10.1371/journal.ppat.1014025

humanproteomics

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GenomicsScientific ReportsPeer-reviewedFeb 7, 2020

Generation of light-producing somatic-transgenic mice using adeno-associated virus vectors

Rajvinder Karda, Ahad A. Rahim, Andrew M.S. Wong…·Simon N. Waddington

The paper develops a method using adeno-associated virus vectors to generate somatic-transgenic mice for non-invasive monitoring of signaling pathways in disease models.

6 citations

mouseexperimental assay

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